Search Repository Universitas Fort De Kock

Drug Related Problems (DRPs) adalah suatu keadaan terkait dengan terapi obat
yang bertentangan dengan kemampuan pasien untuk dapat mencapai tujuan yang
optimal. Hipertensi adalah kondisi ketika tekanan darah berada pada angka
140/90 mmHg atau lebih. Penelitian ini bertujuan untuk mengetahui kejadian
DRPs terhadap keberhasilan terapi pasien hipertensi di Rumah Sakit Achmad
Mochtar Bukittinggi tahun 2023. Penelitian ini bersifat kuantitatif, pengambilan
data secara retrospektif. Pengambilan sampel secara Simple Random Sampling
dengan menggunakan rumus slovin didapatkan sampel sebanyak 91 sampel.
Penelitian ini menggunakan uji Chi square test SPSS. Hasil penelitian
sosiodemografi didapatkan yaitu jenis kelamin perempuan sebanyak (51,6%),
mempunyai riwayat pendidikan SMA sebanyak (53,8%), dan memilikia pekerjaan
sebanyak (61,5 %). Dan analisa univariat didapatkan yaitu tidak adanya indikasi
yang tidak diobati sebanyak (87,9%), tidak ada pemilihan obat yang tidak tepat
sebanyak (86,8%), adanya dosis subterapeutik sebanyak (98,9%), tidak ada
overdosis sebanyak (100%), ada interaksi obat sebanyak (83,5%), dan tidak ada
obat tanpa indikasi sebanyak (81,3%) serta keberhasilan terapi pasien hipertensi
sebanyak (65,9%). Hasil penelitian dengan anilisa bivariat didapatkan (P value
0,008 dan OR 4,95) yaitu terdapat ada hubungan antara obat tanpa indikasi
dengan keberhasilan terapi pasien hipertensi.

Drug Related Problems (DRPs) refer to conditions related to drug therapy that interfere
with a patient's ability to achieve optimal therapeutic outcomes. Hypertension is defined
as a condition in which blood pressure reaches 140/90 mmHg or higher. This study aims
to analyze the occurrence of DRPs and their impact on the success of hypertension
therapy in patients at Achmad Mochtar Hospital, Bukittinggi, in 2023. This research is
quantitative in nature, using retrospective data collection. Sampling was conducted using
Simple Random Sampling and the Slovin formula, resulting in a total of 91 samples. The
data were analyzed using the Chi-Square test in SPSS. The sociodemographic results
showed that the majority of participants were female (51.6%), had a high school
education (53.8%), and were employed (61.5%). Univariate analysis showed that
untreated indications were absent in 87.9% of cases, inappropriate drug selection in
86.8%, subtherapeutic doses were found in 98.9%, no overdose occurred in 100% of
cases, drug interactions were present in 83.5%, and drugs without indication were not
found in 81.3% of cases. The success rate of hypertension therapy was 65.9%. Bivariate
analysis revealed a significant relationship between drugs without indication and
therapeutic success (P value = 0.008; OR = 4.95), indicating that drugs given without
proper indication negatively impact the success of hypertension therapy.