Search Repository Universitas Fort De Kock

Daun alpukat (Persea americana Mill.) mengandung flavonoid dan tanin yang
berpotensi sebagai imunomodulator. Penelitian ini bertujuan mengevaluasi
pengaruh fraksi etil asetat daun alpukat terhadap profil darah lengkap tikus putih
jantan galur Wistar serta menentukan dosis yang optimal. Desain penelitian
menggunakan true experimental dengan metode pre-post test control. Tikus dibagi
dalam empat kelompok, yaitu kontrol, dosis 150 mg, 300 mg, dan 600 mg yang
diberikan secara oral selama 14 hari. Parameter hematologi yang diukur meliputi
hemoglobin, eritrosit, hematokrit, trombosit, limfosit, dan monosit. Analisis data
dilakukan dengan uji Kruskal-Wallis. Hasil penelitian menunjukkan bahwa
pemberian fraksi etil asetat daun alpukat pada dosis 150, 300, dan 600 mg tidak
memberikan perbedaan bermakna (p>0,05) pada kadar hemoglobin, eritrosit,
trombosit, limfosit, dan monosit. Namun, terdapat perbedaan signifikan (p

avocado leaves (Persea americana Mill) contain flavonoids and tannins that have
the potential as immununomodulators. This study aims to evaluate the effect of the
ethyl acetate fraction of avocado leaves on the complete blood profile of male white
Wistar rats and determine the optimal dose. The study design used a true
experimental with a pre-post text control method. Rats were divided into four
groups, namely control, doses of 150 mg, 300 mg and 600 mg given orally for 14
days. Hematological parameters measured included hemoglobin, erythrocytes,
hematocrit platelets, lymphocytes, and monocytes. Data analysis was performed
using the Kruskal-Wallis test. The results showed that administration of the ethyl
acetate fraction of avocado leaves at doses of 150, 300 and 600 mg did not provide
significant differences (p>0.05) in hemoglobin, erythrocyte, platelet, lymphocyte,
and monocyte levels. However, there was a significant difference (p