Search Repository Universitas Fort De Kock

Osteoartritis merupakan penyakit sendi degeneratif yang ditandai dengan adanya kerusakan pada kartilago persendian yang melindungi ujung tulang dan sering terjadi pada pasien lanjut usia. Obat-obatan yang sering digunakan pada terapi osteoartritis adalah parasetamol, antiinflamasi non steroid (AINS), kortikosteroid, dan suplemen. Penelitian ini bertujuan untuk menganalisis Drug Related Problems potensial kategori ketidaksesuaian dosis dan interaksi obat pada pasien lanjut usia osteoartritis di salah satu Puskesmas Kabupaten Agam yang dilaksanakan pada bulan juni 2022. Penelitian ini merupakan penelitian deskriptif dengan penelusuran data secara retrospektif. Data yang dikumpulkan dari rekam medis pasien lanjut usia osteoartritis pada periode 2020 dan 2021. Sampel penelitian sebanyak 107 rekam medis responden osteoartritis yang diambil secara total sampling. Data interaksi obat dianalisis menggunakan Drug Interaction Checker (software dari Medscape dan drugs.com) dan buku referensi Stockleys Drug Interaction 9th edition dan Drug Interaction Facts. Sedangkan kesesuaian regimen dosis, menggunakan Geriatric Dosage Handbook 16th edition, Drug Information Handbook ( DIH ) 21st edition, AHFS Drug Information Essentials (2011), IONI 2017. Hasil penelitian menunjukkan bahwa dari 107 responden terdapat adanya ketidaksesuaian dosis obat kategori dosis kurang 30 kasus (28,04%), frekuensi rendah 37 kasus (34,57%), dan potensial interaksi obat berdasarkan tingkat keparahan major 6 kasus (5,6%), moderat 26 kasus (24,3%), dan minor 6 kasus (5,6%). Disimpulkan bahwa adanya kejadian Drug Related Problems (DRPs) kategori potensi interaksi obat dan ketidaksesuaian dosis pada pasien lanjut usia osteoartritis di salah satu Puskesmas Kabupaten Agam.

Osteoarthritis is a degenerative joint disease characterized by damage to the joint cartilage that protects the ends of bones and often occurs in elderly patients. Drugs that are often used in the treatment of osteoarthritis are paracetamol, non-steroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and supplements. This study aimed to analyze potential Drug Related Problems in the category of dose mismatch and drug interactions in elderly osteoarthritis patients at one of the Agam District Community Health Centers which was carried out in June 2022. This study was a descriptive study with a retrospective data search. Data were collected from medical records of elderly patients with osteoarthritis in the period 2020 and 2021. The sample of the study was 107 medical records of osteoarthritis respondents who were taken by total sampling. Drug interaction data were analyzed using Drug Interaction Checker (software from Medscape and drugs.com) and Stockley's Drug Interaction 9th edition and Drug Interaction Facts reference books. While the suitability of the dosage regimen, using the Geriatric Dosage Handbook 16th edition, Drug Information Handbook (DIH) 21st edition, AHFS Drug Information Essentials (2011), IONI 2017. The results showed that from 107 respondents there is a drug dose mismatch in the less dose category 30 cases (28.04%), low frequency 37 cases (34.57%), and potential drug interactions based on the severity of the major 6 cases (5.6%), moderate 26 cases (24.3%), and minor 6 cases (5.6%). It was concluded that the incidence of Drug Related Problems (DRPs) in the category of potential drug interactions and dose mismatches in elderly patients with osteoarthritis in one of the Community Health Centers in Agam Regency.