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Data WHO (2021), pada bulan Oktober 2021 sebesar 34,3% dari populasi dunia telah diberikan vaksin lengkap. Data DinKes Kab. Solok Selatan pencapaian vaksin pertama sebesar 31% dan vaksin kedua sebesar 12,7% dari sasaran sebesar 143.956 orang. Penelitian ini bertujuan untuk melihat faktor-faktor yang mempengaruhi persepsi masyarakat terhadap vaksin Covid-19. Jenis penelitian adalah analitik dengan desain penelitian cross sectional study yang dilakukan di Jorong Sungai Lambai Timur Kecamatan Sangir Kabupaten Solok Selatan pada bulan Desember 2021-Januari 2022. Populasi semua masyarakat yang berjumlah 528 orang dengan teknik pengambilan sampel accidental samplingberjumlah 84 orang. Data dikumpulkan menggunakan kuesioner dan dianalisis secara univariat dan bivariat dengan uji statistik chi-square. Hasil didapatkan 41,7% masyarakat memiliki persepsi negatif. sebesar 44,0% masyarakat memiliki tingkat pengetahuan rendah. Sebesar 39,3% masyarakat memiliki tingkat pendidikan rendah. Sebesar 34,5% masyarakat memiliki budaya.Sebesar 42,9% masyarakat belum melaksanakan vaksinasi Covid-19. Terdapat hubungan tingkat pengetahuan (p = 0,0005 dan OR = 6,042), tingkat pendidikan (p
= 0,031 dan OR = 2,969), budaya (p = 0,012 dan OR = 3,658), dan pelaksanaan vaksinasi Covid-19 (p = 0,0005 dan OR = 6,727) dengan persepsi masyarakat. Dapat disimpulkan bahwa ada hubungan tingkat pengetahuan, tingkat pendidikan, budaya, dan pelaksanaan vaksinasi Covid-19 dengan persepsi masyarakat. Untuk itu disarankan kepada masyarakat agar mencari informasi-informasi yang benar tentang vaksinasi Covid-19 dan bisa membedakan informasi yang benar dan informasi yang salah, sehingga masyarakat tidak salah dalam mempersepsikan tentang vaksin Covid-19.

WHO data (2021), in October 2021 34.3% of the world's population has been given a complete vaccine. District Health Office data. Solok Selatan achieved the first vaccine by 31% and the second vaccine by 12.7% of the target of 143.956 people. This study aims to determine the factors that influence public perception of the Covid-19 vaccine. The type of research used is analytic with a cross sectional study design conducted in Jorong Sungai Lambai Timur, Sangir District, South Solok Regency. The population of all communities which amounted to 528 people with accidental sampling technique was 84 people. The results of the univariate analysis showed that 41.7% of the community
had a negative perception. 44.0% of people have a low level of knowledge. 39.3% of the people have a low level of education. 34.5% of the people have culture. As many as 42.9% of the people have not carried out the Covid-19 vaccination. The results of the statistical test showed that there was a relationship between the level of knowledge (p = 0.0005 and OR = 6.042), education level (p = 0.031 and OR = 2.969), culture (p = 0.012 and OR = 3.658), and the implementation of Covid-19 vaccination ( p = 0.0005 and OR = 6.727) with public perception. It can be concluded that there is a relationship between the level of knowledge, level of education, culture, and implementation of the Covid-19 vaccination with public perception. For this reason, it is recommended that the public seek correct information about the Covid-19 vaccination and be able to distinguish between correct and incorrect information, so that people do not misperceive the Covid-19 vaccine.