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Kejadian HIV di Indonesia tahun 2018 sebanyak 301.959 jiwa. HIV/AIDS ditularkan melalui darah, cairan mani dan vagina serta penggunaan jarum suntik bekas. Tujuan penelitian ini adalah mengetahui gambaran pengetahuan dan sikap remaja terhadap HIV/AIDS di Wilayah kerja Puskesmas tahun 2019. Jenis penilitian ini bersifat deskriptif. Penelitian ini dilakukan di SMAN 3 Kota Bukittinggi di wilayah kerja Puskesmas Guguk Panjang Kota Bukittinggi dan telah dilakukan pada tanggal 30 - 31 Juli 2019. Populasi dalam penilitian ini sebanyak 208 orang dengan teknik pengambilan sampel secara proporsional sampling dengan jumlah sampel sebanyak 68 responden. Pengolahan data dilakukan secara komputerisasi dengan analisis univariat. Hasil penelitian diketahui bahwa dari 68 responden, sebanyak 39 (57%) siswa berpengetahuan kurang, 21 (31%) siswa berpengetahuan cukup dan sebanyak 8 (12%) siswa berpengetahuan baik. Sebanyak 38 (56%) siswa bersikap negatif dan terdapat 30 (44%) siswa bersikap positif. Dapat disimpulkan bahwa pengetahuan remaja SMA kelas 2 terhadap HIV/AIDS masih kurang dan masih bersikap negatif di SMAN 3 Kota Bukittinggi. Maka dari itu diharapkan kepada siswa agar dapat meningkatkan pengetahuan mengenai bahaya HIV/AIDS serta dapat mengurangi sikap negatif terhadap HIV/AIDS.

In Indonesia, HIV cases in 2018 were 301,959 people. HIV / AIDS is transmitted through blood, semen and vagina and the use of used syringes. The purpose of this study was to determine The Description of the Second Grade of Senior High School Students Knowledge and Attitudes toward HIV / AIDS in Guguk Panjang Community Health Center Bukittinggi, 2019. The type of this study was descriptive. It was conducted at SMAN 3 Bukittinggi City in the working area of Guguk Panjang Community Health Center in Bukittinggi on July 30 - 31 2019. The populations were 208 people. By using proportional sampling technique, 68 respondents were chosen as the samples. The data were analyzed by computerization by using univariate analysis. The results of this study showed that 39 (57%) students had lack of knowledge. Then, 21 (31%) of them had sufficient knowledge. Next, 8 (12%) of students had good knowledge. After that, 38 (56%) of them had negative attitude and 30 (44%) students had positive attitude. It can be concluded that the knowledge of senior high school students about HIV / AIDS is lack and they have negative attitude about it. Therefore, it is expected to the students to increase their knowledge about the dangers of HIV / AIDS and to reduce negative attitudes towards HIV / AIDS.