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Cover Analysis of Drug Related Problems (DRPs) and Their Impact on the Success of Outpatient Hypertension Therapy at Achmad Mochtar Hospital, Bukittinggi, in 2023
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Skripsi 2025

Analysis of Drug Related Problems (DRPs) and Their Impact on the Success of Outpatient Hypertension Therapy at Achmad Mochtar Hospital, Bukittinggi, in 2023

Penulis
Mayang Sari
Pembimbing
Evi Hasnita
Jenis repository
Skripsi
Tahun
2025
Fakultas
Fakultas Ilmu Kesehatan
Program studi
S1 Farmasi
Metode penelitian
—
Jenis metode
—
Variabel
—
Sumber dana
—
Lokasi/wilayah penelitian
— (Kota Bukittinggi, Sumatera Barat)
Dipublikasikan
05 Februari 2026

Abstrak

Drug Related Problems (DRPs) adalah suatu keadaan terkait dengan terapi obat yang bertentangan dengan kemampuan pasien untuk dapat mencapai tujuan yang optimal. Hipertensi adalah kondisi ketika tekanan darah berada pada angka 140/90 mmHg atau lebih. Penelitian ini bertujuan untuk mengetahui kejadian DRPs terhadap keberhasilan terapi pasien hipertensi di Rumah Sakit Achmad Mochtar Bukittinggi tahun 2023. Penelitian ini bersifat kuantitatif, pengambilan data secara retrospektif. Pengambilan sampel secara Simple Random Sampling dengan menggunakan rumus slovin didapatkan sampel sebanyak 91 sampel. Penelitian ini menggunakan uji Chi square test SPSS. Hasil penelitian sosiodemografi didapatkan yaitu jenis kelamin perempuan sebanyak (51,6%), mempunyai riwayat pendidikan SMA sebanyak (53,8%), dan memilikia pekerjaan sebanyak (61,5 %). Dan analisa univariat didapatkan yaitu tidak adanya indikasi yang tidak diobati sebanyak (87,9%), tidak ada pemilihan obat yang tidak tepat sebanyak (86,8%), adanya dosis subterapeutik sebanyak (98,9%), tidak ada overdosis sebanyak (100%), ada interaksi obat sebanyak (83,5%), dan tidak ada obat tanpa indikasi sebanyak (81,3%) serta keberhasilan terapi pasien hipertensi sebanyak (65,9%). Hasil penelitian dengan anilisa bivariat didapatkan (P value 0,008 dan OR 4,95) yaitu terdapat ada hubungan antara obat tanpa indikasi dengan keberhasilan terapi pasien hipertensi. Abstract (EN): Drug Related Problems (DRPs) refer to conditions related to drug therapy that interfere with a patient's ability to achieve optimal therapeutic outcomes. Hypertension is defined as a condition in which blood pressure reaches 140/90 mmHg or higher. This study aims to analyze the occurrence of DRPs and their impact on the success of hypertension therapy in patients at Achmad Mochtar Hospital, Bukittinggi, in 2023. This research is quantitative in nature, using retrospective data collection. Sampling was conducted using Simple Random Sampling and the Slovin formula, resulting in a total of 91 samples. The data were analyzed using the Chi-Square test in SPSS. The sociodemographic results showed that the majority of participants were female (51.6%), had a high school education (53.8%), and were employed (61.5%). Univariate analysis showed that untreated indications were absent in 87.9% of cases, inappropriate drug selection in 86.8%, subtherapeutic doses were found in 98.9%, no overdose occurred in 100% of cases, drug interactions were present in 83.5%, and drugs without indication were not found in 81.3% of cases. The success rate of hypertension therapy was 65.9%. Bivariate analysis revealed a significant relationship between drugs without indication and therapeutic success (P value = 0.008; OR = 4.95), indicating that drugs given without proper indication negatively impact the success of hypertension therapy.

Kata Kunci

Hipertensi Keberhasilan Terapi DRPs